Prof. Joyoti Basu
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Recent Submissions
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Protein-4.2 association with band 3 (AE1, SLCA4) in Xenopus oocytes: Effects of three natural protein-4.2 mutations associated with hemolytic anemia
(AMER SOC HEMATOLOGY, 2005-05-15)We have investigated the effects of coexpression of protein 4.2 and three protein-4.2 variants with band 3 in the Xenopus oocyte expression system. Normal protein 4.2 increased band-3-specific chloride transport in the ... -
TLR4-dependent NF-κB activation and mitogen- and stress-activated protein kinase 1-triggered phosphorylation events are central to Helicobacter pylori peptidyl prolyl cis-, trans-isomerase (HP0175)-mediated induction of IL-6 release from macrophages
(AMER ASSOC IMMUNOLOGISTS, 2006-12-01)Helicobacter pylori infection is associated with the local production of chemokines and cytokines, of which IL-6 is overexpressed at the margin of gastric ulcer in H. pylori-positive gastritis. Cells of the monocytic lineage ... -
Interaction between FtsW and penicillin-binding protein 3 (PBP3) directs PBP3 to mid-cell, controls cell septation and mediates the formation of a trimeric complex involving FtsZ, FtsW and PBP3 in mycobacteria
(BLACKWELL PUBLISHING, 2006-12-01)In bacteria, biogenesis of cell wall at the division site requires penicillin-binding protein 3 (PBP3) (or FtsI). Using pull-down, bacterial two-hybrid, and peptide-based interaction assays, we provide evidence that FtsW ... -
Positive feedback and noise activate the stringent response regulator rel in mycobacteria
(PUBLIC LIBRARY SCIENCE, 2008-03-12)Phenotypic heterogeneity in an isogenic, microbial population enables a subset of the population to persist under stress. In mycobacteria, stresses like nutrient and oxygen deprivation activate the stress response pathway ... -
Helicobacter pylori Protein HP0175 Transactivates Epidermal Growth Factor Receptor through TLR4 in Gastric Epithelial Cells
(AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY, 2008-11-21)The pathophysiology of Helicobacter pylori-associated gastroduodenal diseases, ulcerogenesis, and carcinogenesis is intimately linked to activation of epidermal growth factor receptor (EGFR) and production of vascular ... -
RseA, the SigE specific anti-sigma factor of Mycobacterium tuberculosis, is inactivated by phosphorylation-dependent ClpC1P2 proteolysis
(WILEY-BLACKWELL, 2010-02)Central to the response of Mycobacterium tuberculosis to environmental stress is the regulation of genes under the control of alternative sigma factors. Sigma E of M. tuberculosis plays an important role in the intracellular ...
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