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Structural characterization of an immunoenhancing heteroglycan isolated from an aqueous extract of an edible mushroom, Lentinus squarrosulus (Mont.) Singer

dc.contributor.authorBhunia, Sanjoy Kumar
dc.contributor.authorDey, Biswajit
dc.contributor.authorMaity, Kankan K.
dc.contributor.authorPatra, Sukesh
dc.contributor.authorMandal, Soumitra
dc.contributor.authorMaiti, Swatilekha
dc.contributor.authorMaiti, Tapas K.
dc.contributor.authorSikdar, Samir Ranjan
dc.contributor.authorIslam, Syed S.
dc.date.accessioned2012-11-16T09:35:28Z
dc.date.available2012-11-16T09:35:28Z
dc.date.issued2010-11-22
dc.identifier.citationBhunia SK, Dey B, Maity KK, Patra S, Mandai S, Maiti S, Maiti TK, Sikdar S R and Islam SS (201 0) Structural characterization of an immunoenhancing heteroglycan isolated from an aqueous extract of an edible mushroom, Lentinus squarrosulus (Mont.) Singer. Carbohydr Res 345:2542-2549.en_US
dc.identifier.issn0008-6215
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dc.descriptionDOI: 10.1016/j.carres.2010.09.015en_US
dc.description.abstractA water-soluble polysaccharide, isolated from the hot water extract of the fruiting bodies of an edible mushroom, Lentinus squarrosulus (Mont.) Singer was found to contain D-galactose, L-fucose, and D-glucose in a molar ratio of nearly 1:1:5. Structural investigation of the polysaccharide was carried out using acid hydrolysis, methylation analysis, periodate oxidation study, and NMR experiments (1H, 13C, DQF-COSY, TOCSY, NOESY, ROESY, HMQC, and HMBC). On the basis of above-mentioned experiments, the structure of the repeating unit of the polysaccharide was established as: This polysaccharide showed macrophage as well as splenocyte and thymocyte activation.en_US
dc.description.sponsorshipDST, Government of India SR/SI/OC-52/2006 CSIR, New Delhien_US
dc.language.isoenen_US
dc.publisherELSEVIER SCIen_US
dc.subjectLentinus squarrosulus (Mont.) Singeren_US
dc.subjectPolysaccharideen_US
dc.subjectStructureen_US
dc.subjectNMR spectroscopyen_US
dc.subjectSplenocyte and thymocyte activationen_US
dc.subjectWOS:000284520500017en_US
dc.titleStructural characterization of an immunoenhancing heteroglycan isolated from an aqueous extract of an edible mushroom, Lentinus squarrosulus (Mont.) Singeren_US
dc.title.alternativeCarbohydrate Researchen_US
dc.typeArticleen_US


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