Synthesis of the Trisaccharide Repeat of the O-Antigen of Rhanella Aquatilis 1-95

Abstract

A branched trisaccharide containing D-fucose and D-galactofuranose moieties corresponding to the repeating unit of the O-antigen of Rahnella aquatilis 1-95 has been synthesized from the monosaccharide intermediates in a five-step synthesis in an overall 38% yield. All glycosylation steps and protecting group functionalization steps are high yielding.