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An expedient, regioselective synthesis of novel 2-alkylamino- and 2-alkylthiothiazolo[5,4-e]- and -[4,5-g]indazoles and their anticancer potential

dc.contributor.authorChakrabarty, Manas
dc.contributor.authorKundu, Taraknath
dc.contributor.authorArima, Shiho
dc.contributor.authorHarigaya, Yoshihiro
dc.date.accessioned2013-02-08T11:56:05Z
dc.date.available2013-02-08T11:56:05Z
dc.date.issued2008-07-07
dc.identifierFOR ACCESS / DOWNLOAD PROBLEM -- PLEASE CONTACT LIBRARIAN, BOSE INSTITUTE, akc@bic.boseinst.ernet.inen_US
dc.identifier.citationChakrabarty M, Kundu T, Arima S and Harigaya Y (2008) An expedient, regioselective synthesis of novel 2-alkylamino and 2-alkylthiothiazolo[5,4-e]- and-[ 4,5-g]indazoles and their anticancer potential. Tetrahedron 64 (28), 6711-6723.en_US
dc.identifier.issn0040-4020
dc.identifier.uri1.Full Text Link ->en_US
dc.identifier.urihttp://ac.els-cdn.com/S0040402008008661/1-s2.0-S0040402008008661-main.pdf?_tid=42bdd01a-71e7-11e2-98c2-00000aacb35f&acdnat=1360325064_593d13a38fa7167753332666b539f586en_US
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dc.identifier.uri2.Scopus : Citation Link ->en_US
dc.identifier.urihttp://www.scopus.com/record/display.url?eid=2-s2.0-45449090774&origin=resultslist&sort=plf-f&src=s&st1=An+expedient%2c&nlo=&nlr=&nls=&sid=728492907C7639E9E6E70CA802473A57.WeLimyRvBMk2ky9SFKc8Q%3a640&sot=b&sdt=sisr&sl=18&s=ALL%28An+expedient%2c%29&ref=%28%28An+expedient%2c+regioselective+synthesis+of+novel%29%29+AND+%28An+expedient%2c+regioselective+synthesis+of+novel+2-alkylamino%29&relpos=21&relpos=1&searchTerm=%28ALL%28An+expedient%2C%29%29+AND+%28%28An+expedient%2C+regioselective+synthesis+of+novel%29%29+AND+%28An+expedient%2C+regioselective+synthesis+of+novel+2-alkylamino%29en_US
dc.descriptionDOI: 10.1016/j.tet.2008.05.009en_US
dc.description.abstractSeveral novel 2-alkylamino- and 2-alkylthiothiazolo[5,4-e]- and -[4,5-g]indazoles and their 6-alkyl and 8-alkyl derivatives have been synthesised in high overall yields starting from 5-nitro and 6-nitro-indazoles in a three-step route involving the regioselective cyclisation of thioureidoindazoles and indazolyl dithiocarbamates as the key steps. Some assorted thiazoloindazoles have been screened for anticancer properties, which demonstrated the anticancer potential of at least one product, justifying its further follow-up.en_US
dc.language.isoenen_US
dc.publisherPERGAMON-ELSEVIERen_US
dc.subjectthiazolo[5,4-e]- and -[4,5-g]indazolesen_US
dc.subjectanticanceren_US
dc.subjectregioselective synthesisen_US
dc.subjectthioureidoindazolesen_US
dc.subjectindazolyl dithiocarbamatesen_US
dc.subjectbromine in acetic aciden_US
dc.subjectWOS:000257500500015en_US
dc.titleAn expedient, regioselective synthesis of novel 2-alkylamino- and 2-alkylthiothiazolo[5,4-e]- and -[4,5-g]indazoles and their anticancer potentialen_US
dc.title.alternativeTETRAHEDRONen_US
dc.typeArticleen_US


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