Facile synthesis of a tetrasaccharide corresponding to the capsular polysaccharide of Streptococcus pneumoniae type 15B

Abstract

A convergent synthetic approach is presented for the straightforward synthesis of the tetrasaccharide fragment of the capsular polysaccharide of Streptococcus pneumoniae type 15B. Coupling of a disaccharide thioglycoside donor with a disaccharide acceptor furnished the required tetrasaccharide in excellent yield.