Cloning of tubulin genes of vigna radiata(mung bean) and studies of their expression during germination.
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- Thesis (Biochemistry) [118]
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Sulfonamide drugs binding to the colchicine site of tubulin: Thermodynamic analysis of the drug-tubulin interactions by isothermal titration calorimetry
Banerjee, M.; Poddar, A.; Mitra, G.; Surolia, A.; Owa, T.; Bhattacharyya, Bhabatarak (AMER CHEMICAL SOC, 2005-01-27)The discovery of several sulfonamide drugs paved the way toward the synthesis of 6 (N-12-[(4-hydroxyphenyl)amino]-3-pyridinyl]-4-methoxybenzenesulfonamide: E7010) and 7 (N-(3fluoro-4-methoxyphenyl)pentafluorobenzenesulfonamide, ... -
-NH-dansyl isocolchicine exhibits a significantly improved tubulin-binding affinity and microtubule inhibition in comparison to isocolchicine by binding tubulin through its A and B rings
Das, L.; Datta, A. B.; Gupta, S.; Poddar, A.; Sengupta, S.; Janik, M. E.; Bhattacharya, Bhabatarak (AMER CHEMICAL SOC, 2005-03-08)Structure-activity relationship studies have established that the A and C rings of colchicine comprise the minimum structural feature necessary for high affinity drug-tubulin binding. Thus, colchicine acts as a bifunctional ... -
Fluorescence Spectroscopic Methods to Analyze Drug–Tubulin Interactions
Bhattacharyya, Bhabatarak; Kapoor, Sonia; Panda, Dulal (ELSEVIER ACADEMIC PRESS, 2010)Fluorescence spectroscopy has been extensively used to characterize ligand binding to tubulin and microtubules. The inherent advantages of fluorescence spectroscopic methods lie in their ease, sensitivity to local environmental ...

