| dc.contributor.author | Basak, Surajit | |
| dc.contributor.author | Roy, Sujata | |
| dc.contributor.author | Ghosh, Tapash Chandra | |
| dc.date.accessioned | 2013-03-04T09:15:49Z | |
| dc.date.available | 2013-03-04T09:15:49Z | |
| dc.date.issued | 2007-12-22 | |
| dc.identifier | FOR ACCESS / DOWNLOAD PROBLEM -- PLEASE CONTACT LIBRARIAN, BOSE INSTITUTE, akc@bic.boseinst.ernet.in | en_US |
| dc.identifier.citation | Basak S, Roy S and Ghosh. T C (2007) On the origin of synonymous codon usage divergence between thermophilic and mesophilic prokaryotes, FEBS Letters 581, 5825-5830. | en_US |
| dc.identifier.issn | 0014-5793 | |
| dc.identifier.uri | 1.Full Text Link - | |
| dc.identifier.uri | http://www.sciencedirect.com/science/article/pii/S0014579307012057# | en_US |
| dc.identifier.uri | ================================================= | en_US |
| dc.identifier.uri | 2.Scopus : Citation Link -> | en_US |
| dc.identifier.uri | http://www.scopus.com/record/display.url?eid=2-s2.0-37049036395&origin=resultslist&sort=plf-f&src=s&st1=On+the+origin+of+synonymous+codon+usage+divergence+between+thermophilic+and+mesophilic+prokaryotes.&sid=297C7406353BD09892CA16F57703C931.WlW7NKKC52nnQNxjqAQrlA%3a170&sot=b&sdt=b&sl=114&s=TITLE-ABS-KEY%28On+the+origin+of+synonymous+codon+usage+divergence+between+thermophilic+and+mesophilic+prokaryotes.%29&relpos=0&relpos=0&searchTerm=TITLE-ABS-KEY%28On+the+origin+of+synonymous+codon+usage+divergence+between+thermophilic+and+mesophilic+prokaryotes.%29 | en_US |
| dc.description | DOI: 10.1016/j.febslet.2007.11.054 | en_US |
| dc.description.abstract | Synonymous codon usage analysis between thermophilic and mesophilic prokaryotes has gained wide attention in recent years. Although it is known that thermophilic and mesophilic prokaryotes use different subset of synonymous codons, no reason for this difference is known so far. In the present communication, by analyzing a large number of thermophilic and mesophilic prokaryotes, we provide evidence that bias in the selection of synonymous codons between thermophilic and mesophilic prokaryotes is related to differential folding pattern of mRNA secondary structures. Moreover, we observe that error-minimizing property has significant influence in differentiating the synonymous codon usage between thermophilic and mesophilic prokaryotes. Biological implications of these results are discussed. (C) 2007 Federation of European Biochemical Societies | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | ELSEVIER | en_US |
| dc.subject | optimal growth temperature | en_US |
| dc.subject | synonymous codon usage | en_US |
| dc.subject | free folding energy | en_US |
| dc.subject | error minimization | en_US |
| dc.subject | Z-score | en_US |
| dc.subject | WOS:000253488200015 | en_US |
| dc.title | On the origin of synonymous codon usage divergence between thermophilic and mesophilic prokaryotes | en_US |
| dc.title.alternative | FEBS LETTERS | en_US |
| dc.type | Article | en_US |
