Department of Biophysics: Recent submissions
Now showing items 1-20 of 64
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Structural and Functional Studies of Designed Antimicrobial & Anti-Inflammatory Peptides:
(Bose Institute Kolkata, 2020)Multi-drug resistant (MDR) bacteria or superbugs have become a global threat to human life due to their inherent resistance to antibiotics. In this context, antimicrobial peptides (AMPs) have emerged as promising ... -
Faculty Publication List : Dept. of Biophysics, 2012-13
(Bose Institute, Kolkata, 2013) -
Faculty Publication List : Dept. of Biophysics, 2011-12
(Bose Institute, Kolkata, 2012) -
Metal binding to cowpea chlorotic mottle virus using terbium(III) fluorescence (M-T-2003-04)
(SPRINGER-VERLAG, 2003-09)Metals are thought to play a role in the structure of many viruses. The crystal structure of the T=3 icosahedral cowpea chlorotic mottle virus (CCMV) suggests the presence of 180 unique metal-binding sites in the assembled ... -
Homology modeling of allergenic cyclophilins: IgE-binding site and structural basis of cross-reactivity
(ACADEMIC PRESS, 2003-07-25)Cross-reactivity among allergens is of considerable scientific as well as clinical interest. Proteins belonging to the allergenic cyclophilin family share a high degree of sequence homology and are cross-reactive. Until ... -
Fluorescence quenching methods to study protein-nucleic acid interactions
(ACADEMIC PRESS, 2004) -
Monomer and dimer of Chandipura virus unphosphorylated P-protein binds leader RNA differently: Implications for viral RNA synthesis
(ACADEMIC PRESS, 2004-06-18)Interaction of the leader RNA with the unphosphorylated P-protein has been proposed to play a key role in the transcription-replication transition of Chandipura virus, a model rhabdovirus. Electrophoretic mobility shift ... -
GaIR represses gaIP1 by inhibiting the rate-determining open complex formation through RNA polymerase contact: A GaIR negative control mutant
(ACADEMIC PRESS, 2004-11-26)Ga1R represses the galP1 promoter by a DNA looping-independent mechanism. Equilibrium binding of Ga1R and RNA polymerase to DNA, and real-time kinetics of base-pair distortion (isomerization) showed that the equilibrium ... -
Electrostatic potential of nucleotide-free protein is sufficient for discrimination between adenine and guanine-specific binding sites
(ACADEMIC PRESS, 2004-09-17)Despite sharing many common features, adenine-binding and guanine-binding sites in proteins often show a clear preference for the cognate over the non-cognate ligand. We have analyzed electrostatic potential (ESP) patterns ... -
Sequence divergence of Entamoeba histolytica tubulin is responsible for its altered tertiary structure
(ACADEMIC PRESS, 2004-07-02)Atypical microtubular structures of the protozoan parasite Entamoeba histolytica (Eh) have been attributed to amino acid sequence divergence of Eh tubulin. To investigate if this sequence divergence leads to significant ... -
Expanded turn conformations: Characterization and sequence-structure correspondence in alpha-turns with implications in helix folding
(WILEY-BLACKWELL,, 2004-05-01)Like the beta-turns, which are characterized by a limiting distance between residues two positions apart (i, i+3), a distance criterion (involving residues at positions i and i+4) is used here to identify a-turns from a ... -
Small cationic protein from a marine turtle has beta-defensin-like fold and antibacterial and antiviral activity
(WILEY-LISS, 2006-08-01)Egg white of marine turtle Caretta caretta contains a small cationic protein but lacks lysozyme. The protein was sequenced by a combination of sequential Edman degradation, carboxypeptidase digestion, nuclear magnetic ...