DSpace at Bose Institute: Recent submissions
Now showing items 1301-1320 of 2749
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Unfolding and refolding of bovine α-crystallin in urea and its chaperone activity
(SPRINGER, 2007-08-01)We undertook an unfolding and refolding study of alpha(L)-crystallin in presence of urea to explore the breakdown and formation of various levels of structure and to find out whether the breakdown of various levels of ... -
Tumor-induced oxidative stress perturbs nuclear factorr-kappa B activity-augmenting tumor necrosis factor-alpha-mediated T-cell death: Protection by curcumin
(AMER ASSOC CANCER RESEARCH, 2007-01-01)Cancer patients often exhibit loss of proper cell-mediated immunity and reduced effector T-cell population in the circulation. Thymus is a major site of T-cell maturation, and tumors induce thymic atrophy to evade cellular ... -
Reaction of diethyl mesoxalate with active methylene compounds: An interesting outcome
(SCIENTIFIC PUBL-INDIA, 2008-02-01)Diethyl mesoxalate reacts separately with each of Meldrum's acid, indan-1,3-dione and diethyl malonate - all active methylene compounds - on neutral alumina either at room temperature or under microwave irradiation to ... -
Tosic acid-on-silica gel: A cheap and eco-friendly catalyst for a convenient one-pot synthesis of substituted benzimidazoles
(SPRINGER WIEN, 2007-12-01)2-Substituted and 1,2-disubstited benzimidazoles were prepared efficiently from o-phenylenediamines and aryl aldehydes using p-toluenesulphonic acid (5∈mol%)-on-silica gel as a cheap and environmentally benign catalyst. -
One-pot formation of functionalised 2-piperidinones from arylidenecyanoacetates and methanolic ammonia via tandem reactions
(PERGAMON-ELSEVIER SCIENCE LTD, 2007-12-01)Aryl aldehydes react with ethyl cyanoacetate in methanolic ammonium acetate to expeditiously furnish, besides high yields of arylidenecyanoacetates, 4,6-diaryt-3,5-dicyano-5-ethoxycarbonyl-2-piperidinones in low yields. ... -
TNF-alpha induction of GM2 expression on renal cell carcinomas promotes T cell dysfunction
(AMER ASSOC IMMUNOLOGISTS, 2007-05-15)Previous studies from our laboratory demonstrated the role of tumor-derived gangliosides as important mediators of T cell apoptosis, and hence, as one mechanism by which tumors evade immune destruction. In this study, we ... -
Structural studies on Vibrio cholerae ToxR periplasmic and cytoplasmic domains
(ELSEVIER, 2007-10)The transcription activator ToxR controls the expression of cholera toxin, pilus colonization factor and outer membrane protein in Vibrio cholerae. It binds to the 5'-TTTTGAT-3' tandernly repeated DNA sequence in the cholera ... -
Black tea-induced decrease in IL-10 and TGF-ss of tumor cells promotes Th1/Tc1 response in tumor bearer.
(LAWRENCE ERLBAUM ASSOC INC-TAYLOR & FRANCIS, 2007)Several lines of evidence support that impairment of host immune function by tumor may be related to several strategies of tumor escape from immunosurveillance. We found that in Ehrlich's ascites carcinoma (EAC)-bearing ... -
Analysis of processivity of mungbean dideoxynucleotide-sensitive DNA polymerase and detection of the activity and expression of the enzyme in the meristematic and meiotic tissues and following DNA damaging agent
(ELSEVIER, 2008-07-01)Analysis of the processivity of mungbean ddNTP-sensitive DNA polymerase showed the incorporation of similar to 35-40 nucleotides per binding event in the replication assays involving M13 ss DNA template with 5'-labeled ... -
A Keggin heteropoly acid as an efficient catalyst for an expeditious, one-pot synthesis of 1-methyl-2-(hetero)arylbenzimidazoles
(PERGAMON-ELSEVIER SCIENCE LTD, 2007-07-23)The Keggin heteropoly acid, silicotungstic acid, H4SiW12O40, has been demonstrated to be highly efficient for an expeditious, one-pot synthesis of 1-methyl-2-(hetero)arylbenzimidazoles from N-methyl-1,2-phenylenediamine ... -
Curcumin prevents tumor-induced T cell apoptosis through Stat-5a-mediated Bcl-2 induction
(AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 2007-06-01)Patients with advanced cancer exhibit multifaceted defects in their immune capacity, which are likely to contribute to an increased susceptibility to infections and disease progression. We demonstrated earlier that curcumin ... -
Differential transcriptional regulation of banana sucrose phosphate synthase gene in response to ethylene, auxin, wounding, low temperature and different photoperiods during fruit ripening and functional analysis of banana SPS gene promoter
(SPRINGER, 2008-12)Sucrose phosphate synthase (SPS) (EC 2.3.1.14) is the key regulatory component in sucrose formation in banana (Musa acuminata subgroup Cavendish, cv Giant governor) fruit during ripening. This report illustrates differential ... -
Black tea-induced amelioration of hepatic oxidative stress through antioxidative activity in EAC-bearing mice
(BEGELL HOUSE INC, 2007)It is recognized that during cancer, the disease itself as well as many of the anticancer drugs in use produce undesirable side effects such as hepatotoxicity. We have already demonstrated the antitumor and immunorestoring ... -
Characterization of transcriptional profiles of MA-ACS1 and MA-ACO1 genes in response to ethylene, auxin, wounding, cold and different photoperiods during ripening in banana fruit
(ELSEVIER, 2008-12)The ripening-specific genes MA-ACS1 (Musa acuminata ACC synthase1) and MA-ACO1 (M. acuminata ACC oxidase 1) are regulated in response to a wide variety of factors. Here, we have studied the differential transcript accumulation ... -
Renal cell carcinoma tumors induce T cell apoptosis through receptor-dependent and receptor-independent pathways(M-T-ANR-2007-08)
(2008-04-01)Tumors can promote their own progressive growth by inducing T cell apoptosis. Though previous studies suggested that tumor-mediated T cell killing is receptor dependent, we recently showed that tumor gangliosides also ... -
General relativistic effects on the conversion of nuclear to two-flavor quark matter in compact stars
(AMER PHYSICAL SOC, 2007-11-19)We investigate the general relativistic (GR) effects on the conversion from nuclear to two-flavor quark matter in compact stars, both static as well as rotating. We find that GR effects lead to qualitative differences in ... -
Rotating quark star in chiral colour dielectric model
(WORLD SCIENTIFIC PUBL CO PTE LTD, 2007-05-10)The properties of rotating quark star are studied using the equation of state obtained from chiral colour dielectric model. The results are compared with those obtained from MIT bag model equation of state. The frequencies ... -
AC conductivity and dielectric relaxation in CaMg1 / 3 Nb2 / 3 O3
(PERGAMON-ELSEVIER SCIENCE LTD, 2008-05-06)The complex perovskite oxide calcium magnesium niobate, CaMg1/3Nb2/3O3 (CMN) is synthesized by a solid-state reaction technique. Dielectric spectroscopy is applied to investigate the electrical properties of CMN in a ... -
Dielectric relaxation and electronic structure of Ca (Fe1 2 Sb1 2) O3
(AMER PHYSICAL SOC, 2007-10-23)The frequency-dependent dielectric relaxation of calcium-iron-antimonate [Ca (Fe1 2 Sb1 2) O3] (CFS) ceramic, synthesized by a solid-state reaction technique is investigated in the temperature range from 143 to 463 K by ... -
Structural and low frequency dielectric studies of conducting polymer nanocomposites
(NATL INST SCIENCE COMMUNICATIO, 2007-08-01)The intrinsically conducting polymer (ICP), polyaniline (PANI) has been synthesized by chemical polymerization process with the help of water soluble support polymer poly (vinyl pyrrolidone) (PVP). The X-ray diffraction ...