DSpace at Bose Institute: Recent submissions
Now showing items 1741-1760 of 2749
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Discriminating the native structure from decoys using scoring functions based on the residue packing in globular proteins
(BIOMED CENTRAL, 2009-12-28)Background: Setting the rules for the identification of a stable conformation of a protein is of utmost importance for the efficient generation of structures in computer simulation. For structure prediction, a considerable ... -
Structural study of carboxylesterase from hyperthermophilic bacteria Geobacillus stearothermophilus by molecular dynamics simulation
(ELSEVIER SCIENCE, 2010-06)Carboxylesterases are ubiquitous enzymes with important physiological, industrial and medical applications such as synthesis and hydrolysis of stereo specific compounds, including the metabolic processing of drugs, and ... -
Investigation of the molecular evolution of nitrogen fixation using nucleotide triplet based condensed matrix method
(IJIB, 2010)Evolutionary history of nitrogen fixation has been retraced by analyzing nif H, D and K genes, and whole genomes from cyanobacteria, proteobacteria, clostridia, actinobacteria, green sulfur bacteria and archaea using ... -
Role of Protein Flexibility in the Discovery of New Drugs
(WILEY-BLACKWELL, 2011-02)Proteins have inherent flexibility, and this plays a critical role in a vast array of biological functions, including ligand binding. Structure-based drug design (SBDD) strategies incorporate biomolecular structures with ... -
Moleculardynamicssimulations of Aβfibrilinteractions with β-sheetbreakerpeptides
(ELSEVIER SCIENCE, 2010-11)Accumulation and aggregation of the 42-residue amyloid-β (Aβ) protein fragment, which originates from the cleavage of amyloid precursor protein by β and γ secretase, correlates with the pathology of Alzheimer's disease ... -
Functional Characterization and Expression Profiling of Human Induced Pluripotent Stem Cell- and Embryonic Stem Cell-Derived Endothelial Cells
(MARY ANN LIEBERT, 2011-10)With regard to human induced pluripotent stem cells (hiPSCs), in which adult cells are reprogrammed into embryonic-like cells using defined factors, their functional and transcriptional expression pattern during endothelial ... -
Prediction of Active Site Cleft Using Support Vector Machines
(AMER CHEMICAL SOC, 2010-12)Computational tools are available today for the detection and delineation of the clefts and cavities in protein 3D structure and ranking them on the basis of probable binding site clefts. There is a need to improve the ... -
Conserved residue clusters at protein-protein interfaces and their use in binding site identification
(BIOMED CENTRAL, 2010-05-27)Background: Biological evolution conserves protein residues that are important for structure and function. Both protein stability and function often require a certain degree of structural co-operativity between spatially ... -
Plant chimeras and their role in development of new ornamental varieties
(Indian Society of Ornamental Horticulture (ISOH), 2010)This will be Available Shortly… -
The Subunit Interfaces of Weakly Associated Homodimeric Proteins
(ACADEMIC PRESS, 2010-04-23)We analyzed subunit interfaces in 315 homodimers with an X-ray structure in the Protein Data Bank, validated by checking the literature for data that indicate that the proteins are dimeric in solution and that, in the case ... -
Carbon metabolism in Rhizobium sp. (Cicer arietinum L.) BICC 620 under anaerobic condition and in its bacteroids
(BOTANICAL SOCIETY OF BENGAL, 2009)This will be Available Shortly… -
Library Consortia : Some Issues
(Journal of Library and Information Science, 2010)No abstract available -
Digital Library System : with reference to Consortia
(Not Available, 2010-01-14)No abstract available -
On nucleotide solvent accessibility in RNA structure
(ELSEVIER SCIENCE, 2010-09-01)Sequence dependence of solvent accessibility in globular and membrane proteins is well established. However, this important structural property has been poorly investigated in nucleic acids. On the other hand investigation ... -
Insights into the genomic features and evolutionary impact of the genes configuring duplicated pseudogenes in human
(ELSEVIER SCIENCE, 2010-09-24)Pseudogenes, regarded as 'genomic fossils', are DNA sequences resembling functional genes in perspective of sequence homology but completely non-functional. In this study, we explored the unique characteristic features of ... -
Studies on Makhana (Euryale ferox Salisbury)
(INDIAN ACAD SCIENCES, 2010-09-25)Makhana (Euryale ferox Salisbury) grows as an exclusive aquatic cash crop in shallow water bodies in north Bihar and lower Assam regions of India. It has nutritional and medicinal properties and supports cottage industry. ... -
Synthesis of penta- and hexasaccharide fragments corresponding to the O-antigen of Escherichia coli O150
(PERGAMON-ELSEVIER SCIENCE, 2010-09-08)The chemical synthesis of a pentasaccharide and a hexasaccharide corresponding to the O-antigen of Escherichia coli O150 has been achieved using sequential glycosylation and [3+3] block glycosylation strategies. Suitably ... -
Protein Connectivity and Protein Complexity Promotes Human Gene Duplicability in a Mutually Exclusive Manner
(OXFORD UNIV PRESS, 2010-10)It has previously been reported that protein complexity (i.e. number of subunits in a protein complex) is negatively correlated to gene duplicability in yeast as well as in humans. However, unlike in yeast, protein ... -
Potential production and preservation of dahi by Lactococcus lactis W8, a nisin-producing strain
(ELSEVIER SCIENCE BV, 2010-03-01)Lactococcus lactis W8 produced nisin concomitantly while fermenting milk to "dahi", a traditional Indian fermented milk. The activity of nisin was detected at 3 h of fermentation, which increased in parallel to growth of ... -
Efficient synthesis of (6-deoxy-glycopyranosid-6-yl) sulfone derivatives and their effect on Ca 2+-ATPase
(Elsevier Masson, 2010-12)Synthesis of a series of novel (6-deoxy-glycopyranosid-6-yl) sulfone derivatives has been achieved using a general synthetic strategy. Yields were excellent in every case. The synthetic compounds were evaluated for their ...