Department of Chemistry: Recent submissions
Now showing items 21-40 of 173
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Accessibility of the various regions of β-lactoglobulin during thermal unfolding and refolding
(Indian Society for Surface Science and Technology, 2004)Structure of the refolded β-lactoglobulin has been compared with that of native β-lactoglobulin by measuring the accessibility of the various regions of the protein molecule. Site selective fluorescence labelling was ... -
An expedient, regioselective synthesis of 2-alkylamino- and 2-alkylthiothiazolo[5,4-e]indoles
(PERGAMON-ELSEVIER SCIENCE LTD, 2005-04-18)1-Benzenesulfonyl-5-aminoindole 5, prepared from 5-nitroindole 3, was condensed with alkyl isothiocyanates and separately with carbon disulfide and alkyl bromides/iodides to furnish efficiently the corresponding ... -
A new catalytic application of a keggin acid in the synthesis of symmetrical bis(indolyl)alkanes
(PERGAMON-ELSEVIER SCIENCE LTD, 2006-02-01)Silicotungstic acid, H4SiW12O40, an important Keggin heteropoly acid, efficiently catalysed the reaction of indoles with aryl aldehydes in ethyl acetate solution at room temperature to furnish symmetrical bis(indolyl)alkanes ... -
A facile clay-mediated synthesis of 3,3-diindolyl-2-indolinones from isatins
(SCIENCE REVIEWS LTD, 2005-08-01)Dry reaction of isatins (3a, 3b) with indoles (4a-e) on montmorillonite K10 clay at room temperature furnished within minutes 3,3-bis(3'-indolyl)-2-indolinones (1a-f) in high yields. 5-Nitroisatin (3c) furnished, in addition ... -
A novel, expedient synthesis of thiazolo[4,5-c]- and -[5,4-b]carbazoles
(PERGAMON-ELSEVIER SCIENCE LTD, 2004-01-01)A new synthesis of thiazolo[4,5-c]- and -[5,4-b]carbazoles (6a-e, 7a, 8b-e) was accomplished from 3-aminocarbazoles (3a-e) by separate condensations with methyl and phenyl isothiocyanates, followed by oxidative cyclization ... -
Ultraviolet-visible-near infrared and mid-Fourier transform infrared spectroscopic studies of intermolecular interaction in cholesteryl oleyl carbonate in mesophases
(AMER INST PHYSICS, 2006-03-28)Ultraviolet-visible-near infrared (UV-Vis-NIR) and Fourier transform infrared (FTIR) spectroscopic studies are presented of molecular association between like molecules of cholesteryl oleyl carbonate, each containing ... -
IL-32: An emerging player in the immune response network against tuberculosis?
(PUBLIC LIBRARY SCIENCE, 2006-08-01)[No abstract available] -
The RD1-encoded antigen Rv3872 of Mycobacterium tuberculosis as a potential candidate for serodiagnosis of tuberculosis
(BLACKWELL PUBLISHING, 2007-02-01)Tuberculosis (TB) infections in India account for one-third of the global burden, making it important to develop speedy, cost-effective diagnostic tools. This study evaluated recombinant RD1-encoded antigens of Mycobacterium ... -
Execution of macrophage apoptosis by PE_PGRS33 of Mycobacterium tuberculosis is mediated by toll-like receptor 2-dependent release of tumor necrosis factor-α
(AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 2007-01-12)Combating tuberculosis requires a detailed understanding of how mycobacterial effectors modulate the host immune response. The role of the multigene PE family of proteins unique to mycobacteria in the pathogenesis of ... -
TLR4-dependent NF-κB activation and mitogen- and stress-activated protein kinase 1-triggered phosphorylation events are central to Helicobacter pylori peptidyl prolyl cis-, trans-isomerase (HP0175)-mediated induction of IL-6 release from macrophages
(AMER ASSOC IMMUNOLOGISTS, 2006-12-01)Helicobacter pylori infection is associated with the local production of chemokines and cytokines, of which IL-6 is overexpressed at the margin of gastric ulcer in H. pylori-positive gastritis. Cells of the monocytic lineage ... -
Interaction between FtsW and penicillin-binding protein 3 (PBP3) directs PBP3 to mid-cell, controls cell septation and mediates the formation of a trimeric complex involving FtsZ, FtsW and PBP3 in mycobacteria
(BLACKWELL PUBLISHING, 2006-12-01)In bacteria, biogenesis of cell wall at the division site requires penicillin-binding protein 3 (PBP3) (or FtsI). Using pull-down, bacterial two-hybrid, and peptide-based interaction assays, we provide evidence that FtsW ... -
An insight into the molecular basis of salt tolerance of L-myo-inositol 1-P synthase (PcINO1) from Porteresia coarctata (Roxb.) Tateoka, a halophytic wild rice
(AMER SOC PLANT BIOLOGISTS, 2006-04-01)The molecular basis of salt tolerance of L myo-inositol 1-P synthase (MIPS; EC 5.5.1.4) from Porteresia coarctata (Roxb.) Tateoka (PcINO1, AF412340) earlier reported from this laboratory, has been analyzed by in vitro ... -
Surface activity coefficients of spread monolayers of behenic acid salts at air-water interface
(ELSEVIER SCIENCE BV, 2006-11-16)The pressure-area isotherms of ionized monolayers of behenic acid at air-water interface at pH 12.0 have been obtained from the Langmuir film balance experiments under various physico-chemical conditions. The value of the ... -
Excess adsorption on hydrophobic and hydrophilic solid-liquid interfaces: Negative adsorption of electrolytes and urea. Part 2
(NATL INST SCIENCE COMMUNICATION, 2006-12-01)The extent of hydration of charcoal, cationic and anionic resin powders in the presence and absence of some inorganic salts and urea has been studied using isopiestic vapour pressure technique. The shapes of water vapour ... -
Excess adsorption on hydrophobic and hydrophilic solid-liquid interfaces. Positive excess adsorption of non-ionic surfactant. Part 1
(NATL INST SCIENCE COMMUNICATION, 2006-12-01)The extent of adsorption (Gamma(1)(2)) of non-ionic surfactant Tween-20 onto hydrophilic alumina and silica and hydrophobic charcoal surfaces has been measured as a function of surfactant concentration (X-2) in mole fraction ... -
Preparation of dibasic acid-containing soy phospholipids by chemical and enzyme-catalyzed transesterification and evaluation of their surface-active properties
(AMER OIL CHEMISTS SOC A O C S PRESS, 2006-12-01)The preparation of dibasic acid-containing soy phospholipid was made by transesterification reaction with alkyl ester of dibasic acid with both lipase and alkoxide as a catalyst. The extent of incorporation of a dibasic ... -
Differential recognition of natural and nonnatural substrate by molecular chaperone α-crystallin - A subunit exchange study
(JOHN WILEY & SONS INC, 2007-02-05)alpha-Crystallin is a molecular chaperone that recognizes proteins substrates in stress. It binds to the unstable conformer of a large variety of related or unrelated substrates and thus prevents them aggregating and holds ... -
A new catalytic application of a keggin acid in the synthesis of symmetrical bis(indolyl)alkanes
(PERGAMON-ELSEVIER SCIENCE LTD, 2006-02-01)Silicotungstic acid, H4SiW12O40, an important Keggin heteropoly acid, efficiently catalysed the reaction of indoles with aryl aldehydes in ethyl acetate solution at room temperature to furnish symmetrical bis(indolyl)alkanes ... -
Application of sulfamic acid as an eco-friendly catalyst in an expedient synthesis of benzimidazoles
(PERGAMON-ELSEVIER SCIENCE LTD, 2006-05-01)Sulfamic acid, an eco-friendly and zwitterionic solid, proved to be a very efficient catalyst for the reaction of ortho-phenylenediamine with aryl aldehydes in ethanol at room temperature to furnish both 1-arylmethyl-2-aryl- ... -
Mild deprotection of tert-butyl carbamates of NH-heteroarenes under basic conditions
(TAYLOR & FRANCIS INC, 2006)Aqueous methanolic potassium carbonate under reflux has been demonstrated to be a highly effective deprotective agent for the tert -butyl carbamates of indoles, indazoles, carbazole, thiazoloindole, and pyrrole. The method ...