Department of Molecular Medicine -- (Formerly Animal Physiology before 2007): Recent submissions
Now showing items 201-219 of 219
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Synthesis of tri- and pentasaccharide fragments corresponding to the O-antigen of Shigella boydii type 6
(PERGAMON-ELSEVIER SCIENCE, 2010-11-25)A convenient synthetic strategy for the synthesis of the acidic pentasaccharide repeating unit and its trisaccharide fragment corresponding to the O-antigen of Shigella boydii type 6 has been successfully developed A ... -
Mannosylated solid lipid nanoparticles as vectors for site-specific delivery of an anti-cancer drug
(ELSEVIER SCIENCE, 2010-12-20)The purpose of the present study was to investigate the tumor targeting potential of surface tailored solid lipid nanoparticles (SLNs) loaded with an anti-cancer drug doxorubicin HCl (DOX). DOX encapsulating SLNs were ... -
Streptozotocin induced activation of oxidative stress responsive splenic cell signaling pathways: Protective role of arjunolic acid
(ACADEMIC PRESS, 2010-04-15)Present study investigates the beneficial role of arjunolic acid (AA) against the alteration in the cytokine levels and simultaneous activation of oxidative stress responsive signaling pathways in spleen under hyperglycemic ... -
Berberine Chloride Mediates Its Anti-Leishmanial Activity via Differential Regulation of the Mitogen Activated Protein Kinase Pathway in Macrophages
(PUBLIC LIBRARY SCIENCE, 2011-04-05)Background: A complex interplay between Leishmania and macrophages influences parasite survival and necessitates disruption of signaling molecules, eventually resulting in impairment of macrophage function. In this study, ... -
Phytomedicinal Role of Pithecellobium dulce against CCl4-mediated Hepatic Oxidative Impairments and Necrotic Cell Death
(HINDAWI PUBLISHING CORPORATION, 2011)Present study investigates the beneficial role of the aqueous extract of the fruits of Pithecellobium dulce (AEPD) against carbon tetrachloride (CCl4)-induced hepatic injury using a murine model. AEPD has been found to ... -
Nicotine Diminishes Testicular Gametogenesis, Steroidogenesis, and Steroidogenic Acute Regulatory Protein Expression in Adult Albino Rats: Possible Influence on Pituitary Gonadotropins and Alteration of Testicular Antioxidant Status
(OXFORD UNIV PRESS, 2010-08)The present study was done to evaluate the pituitary-testicular activities of rats subjected to chronic nicotine treatment. The testicular key androgenic enzymes activities, plasma and intratesticular testosterone (ITT) ... -
Arabinosylated Lipoarabinomannan-Mediated Protection in Visceral Leishmaniasis through Up-Regulation of Toll-Like Receptor 2 Signaling: An Immunoprophylactic Approach
(OXFORD UNIV PRESS INC, 2010-07-01)Visceral leishmaniasis is characterized by severe immunosuppression of the host cell, resulting in loss of the proinflammatory response. Toll-like receptor 2 (TLR2) is involved in myriad disease forms, including visceral ... -
Ethanol Induces Mouse Spermatogenic Cell Apoptosis In Vivo Through Over-Expression of Fas/Fas-L, p53, and Caspase-3 Along With Cytochrome c Trans location and Glutathione Depletion
(WILEY-LISS, DIV JOHN WILEY & SONS, 2010-09)Although it has been well established that spermatogenic cells undergo apoptosis when treated with ethanol, the molecular mechanisms behind it remain to be investigated. Adult male mice were given intra-peritoneal injection ... -
Comparative study of the antioxidant and reactive oxygen species scavenging properties in the extracts of the fruits of Terminalia chebula, Terminalia belerica and Emblica officinalis
(BIOMED CENTRAL, 2010-05-13)Background: Cellular damage caused by reactive oxygen species (ROS) has been implicated in several diseases, and hence natural antioxidants have significant importance in human health. The present study was carried out to ... -
Faculty Publication List : Dept. of Molecular Medicine, 2010-11
(Bose Institute, 2011) -
Faculty Publication List : Dept. of Molecular Medicine, 2009-10
(Bose Institute, 2010) -
Faculty Publication List : Dept. of Molecular Medicine, 2008-09
(Bose Institute, 2009) -
Faculty Publication List : Dept. of Molecular Medicine, 2007-08
(Bose Institute, 2008) -
Protein kinase catalytic subunit (PKAcat) from bovine lens: purification, characterization and phosphorylation of lens crystallins
(Springer US, 2007-10-01)The purification and functional characterization of protein kinase A catalytic subunit (PKAcat) from bovine lens cytosol has been described. Purification to homogeneity has been achieved by using 100 kDa cut-off membrane ...