DSpace at Bose Institute: Recent submissions
Now showing items 1701-1720 of 2749
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A biological battery
(The Hindu, 2012-11-22) -
Window closes on new theory of particle physics
(The Hindu, 2012-11-22) -
'Lord of the Rings' volcano erupts
(The Hindu, 2012-11-22) -
RecA-Mediated Cleavage of lambda cI Repressor Accepts Repressor Dimers: Probable Role of Prolyl Cis-Trans Isomerization and Catalytic Involvement of H163, K177, and K232 of RecA
(ADENINE PRESS, 2009-10)The λ cI repressor is found to be cleaved in the presence of activated RecA in its DNAbound dimeric form at a rate similar to that in the absence of operator DNA in contrast to previous studies inferring repressor monomer ... -
Synthesis of Tri- and Disaccharide Fragments Related to the O-Antigen of Enteropathogenic Escherichia Coli O158
(TAYLOR & FRANCIS, 2010-01)Chemical synthesis of a tri- and a disaccharide related to the O-antigen of enteropathogenic E. coli O158 was achieved in high yield. In the disaccharide (2), one D-galactosamine unit is present in 1,2-cis-linked and the ... -
First synthesis of a pentasaccharide repeating unit of the O-antigenic polysaccharide from enterohaemorrhagic Escherichia coli O48:H21
(PERGAMON-ELSEVIER SCIENCE, 2009-07-16)A concise synthesis of a pentasaccharide as its 4-methoxyphenyl glycoside, found in the O-antigenic polysaccharide of enterohaemorrhagic Escherichia coli O48:H21 has been achieved for the first time in excellent yield. ... -
Genistein Arrests Cell Cycle Progression of A549 Cells at the G2/M Phase and Depolymerizes Interphase Microtubules through Binding to a Unique Site of Tubulin
(AMER CHEMICAL SOC, 2010-03-02)Genistein (40,5,7-trihydroxyisoflavone), an isoflavone, is a major constituent of soyfoods. It has potential antiproliferative activity against several tumor types. We have examined the effect of genistein on cellular ... -
Synthesis of (6,6 ')-C-Linked Pseudodisaccharides
(TAYLOR & FRANCIS, 2009-11-25)A series of (6,6')-C-linked pseudodisaccharides has been prepared using a general synthetic strategy of olefin metathesis in the presence of Grubbs second-generation catalyst. Yields were excellent in every case. -
Pretransitional phenomena in pure states and in a binary mixture of axially and transversàlly dipolar rodlike molecules of near-identical structures
(ISSST, 2009)Mesophase induction generates strong smectic pretransitional fluctuations in the first three phases of a thermotropic polymorphism: Isotropic → Cholesteric → Chiral Smectic-A → Chiral Smectic-C → Chiral Hexatic Smectic → ... -
Fluorescence Spectroscopic Methods to Analyze Drug–Tubulin Interactions
(ELSEVIER ACADEMIC PRESS, 2010)Fluorescence spectroscopy has been extensively used to characterize ligand binding to tubulin and microtubules. The inherent advantages of fluorescence spectroscopic methods lie in their ease, sensitivity to local environmental ... -
Efficient Synthesis of Two Sialylated Tetrasaccharides Found in Goat Milk
(GEORG THIEME VERLAG KG, 2009-04-17)Two regioisomeric sialylated tetrasaccharides found in goat milk have been obtained in excellent yield by a concise synthesis using a common disaccharide intermediate. Regioselective glycosylations and a minimal number of ... -
A TNF- and c-Cbl-dependent FLIPS-degradation pathway and its function in Mycobacterium tuberculosis-induced macrophage apoptosis
(NATURE, 2009-08)Apoptosis is central to the interaction between pathogenic mycobacteria and host macrophages. Caspase-8-dependent apoptosis of infected macrophages, which requires activation of the mitogen-activated protein (MAP) kinase ... -
HflD, an Escherichia coli protein involved in the lambda lysis-lysogeny switch, impairs transcription activation by lambda CII
(ELSEVIER SCIENCE, 2010-01-15)The CII protein of bacteriophage lambda is the key regulator for the lytic–lysogenic choice of the viral lifecycle. An unstable homotetrameric transcription activator of the three phage promoters pE, pI and paQ, λCII is ... -
Total synthesis of the heptasaccharide repeating unit of the iron-binding exopolysaccharide secreted by Klebsiella oxytoca BAS-10
(PERGAMON-ELSEVIER SCIENCE, 2009-08-12)The first total synthesis of a heptasaccharide found in the iron-binding exopolysaccharide produced by Klebsiella oxytoca BAS-10 has been achieved in excellent yield using a block synthetic strategy. A trisaccharide glycosyl ... -
Synthesis of the Trisaccharide Repeat of the O-Antigen of Rhanella Aquatilis 1-95
(TAYLOR & FRANCIS, 2010-01)A branched trisaccharide containing D-fucose and D-galactofuranose moieties corresponding to the repeating unit of the O-antigen of Rahnella aquatilis 1-95 has been synthesized from the monosaccharide intermediates in a ... -
D M Bose memorial Lecture, 26th November, 2012
(Bose Institute, 2012-11-23)128th Birthday Celebration of Pfof. Debendra Mohan Bose. -
Specific hydrophobic residues in the alpha 4 helix of lambda CII are crucial for maintaining its tetrameric structure and directing the lysogenic choice
(SOC GENERAL MICROBIOLOGY, 2010-01)The CII protein of the temperate bacteriophage l is the decision-making factor that determines the viral lytic/lysogenic choice. It is a homotetrameric transcription activator that recognizes and binds specific direct ... -
Anti-IL-10 mAb protection against experimental visceral leishmaniasis via induction of Th1 cytokines and nitric oxide
(NATL INST SCIENCE COMMUNICATION, 2009-06)Visceral leishmaniasis is characterized by severe immune suppression of the host. This suppression of the host immune system is primarily mediated by the immunosuppressive cytokine Interleukin-10 (IL-10), whose levels are ... -
Synthesis of a tetrasaccharide corresponding to the teichoic acid from the cell wall of Streptomyces sp VKM Ac-2275
(PERGAMON-ELSEVIER SCIENCE, 2009-12-11)A concise chemical synthesis of a tetrasaccharide found in the teichoic acid from the cell wall of Streptomyces sp. VKM Ac-2275 was achieved in high yield. A [2+2] block synthetic strategy has been adopted for the construction ... -
Antagonistic effects Na＋ and Mg2＋ on the structure, function, and stability of mycobacteriophage L1 repressor
(KOREAN SOCIETY BIOCHEMISTRY & MOLECULAR BIOLOGY, 2009-05-31)Temperate mycobacteriophage L1 encodes an unusual repressor (CI) for regulating its lytic-lysogenic switching and, in contrast to the repressors of most temperate phages, it binds to multiple asymmetric operator DNAs. Here, ...